Protein Info for Rru_A0750 in Rhodospirillum rubrum S1H

Annotation: Peptide chain release factor 1 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 354 TIGR00019: peptide chain release factor 1" amino acids 3 to 351 (349 residues), 491.4 bits, see alignment E=7e-152 PF03462: PCRF" amino acids 13 to 199 (187 residues), 217.5 bits, see alignment E=1.6e-68 PF00472: RF-1" amino acids 206 to 316 (111 residues), 150.5 bits, see alignment E=1.9e-48

Best Hits

Swiss-Prot: 100% identical to RF1_RHORT: Peptide chain release factor 1 (prfA) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K02835, peptide chain release factor 1 (inferred from 100% identity to rru:Rru_A0750)

Predicted SEED Role

"Peptide chain release factor 1" in subsystem LMPTP YwlE cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RWE1 at UniProt or InterPro

Protein Sequence (354 amino acids)

>Rru_A0750 Peptide chain release factor 1 (NCBI) (Rhodospirillum rubrum S1H)
MSLEENLSRVVARHDELRALLSTSAGGGEGFVRMSRELADLAPVVEAIGRLDDAKAELAG
ARALLDDPDMRDLAREEVLRLEAEIPALEHGVKLLLLPRDEADDRGVILEVRAGTGGDEA
ALFAGDLLRMYERYAQERGWRFEVMEASDTDIGGIKEASAAISGRGVFARLKFESGVHRV
QRVPVTEGGGRIHTSAATVAVLPEAEEVDVEIEEKDLRIDTYRSQGAGGQHVNTTDSAVR
ITHLPSGVVAQCQDEKSQHKNKAKAMRMLRTKLYDHARQTADDARAEARRVQVGSGDRSE
RIRTYNFPQGRVTDHRIGLTLHRLPEVLAGTALDEVIEPLIAEDQATRMAEIGG