Protein Info for Rru_A0651 in Rhodospirillum rubrum S1H
Annotation: Glutamine amidotransferase class-I (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K07010, putative glutamine amidotransferase (inferred from 100% identity to rru:Rru_A0651)Predicted SEED Role
"Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85)" in subsystem Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. or Folate Biosynthesis or Tryptophan synthesis (EC 2.6.1.85)
MetaCyc Pathways
- superpathway of tetrahydrofolate biosynthesis and salvage (10/12 steps found)
- L-asparagine biosynthesis III (tRNA-dependent) (4/4 steps found)
- glutaminyl-tRNAgln biosynthesis via transamidation (4/4 steps found)
- ammonia assimilation cycle III (3/3 steps found)
- superpathway of tetrahydrofolate biosynthesis (8/10 steps found)
- 4-aminobenzoate biosynthesis I (2/2 steps found)
- L-glutamate biosynthesis I (2/2 steps found)
- L-glutamine degradation I (1/1 steps found)
- L-citrulline biosynthesis (6/8 steps found)
- superpathway of L-citrulline metabolism (8/12 steps found)
- L-glutamate and L-glutamine biosynthesis (4/7 steps found)
- superpathway of candicidin biosynthesis (4/11 steps found)
- superpathway of chorismate metabolism (37/59 steps found)
- chloramphenicol biosynthesis (1/9 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.85
Use Curated BLAST to search for 2.6.1.85
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RWP0 at UniProt or InterPro
Protein Sequence (242 amino acids)
>Rru_A0651 Glutamine amidotransferase class-I (NCBI) (Rhodospirillum rubrum S1H) MTRPVIGITADSEEEGGGYSAMPWYAIRHNYCDSVAKAGGLPVILPHNAEVAEDFLGLID GLLITGGAFDVDPALFGEAHRHQTVVLKQRRTAFELAILRGALAADMPILGICGGQQLLA VALGGRLIQHIPDVIKDGLAHEQPNPRTEVGHEISVTPGSLLHRITGVEVFGVNSAHHQA VESVPAPVIVDARAADGVIEGVEDPSRRFCLGVQWHPEYAISAADTAIFDAFVAASRGGE GA