Protein Info for Rru_A0627 in Rhodospirillum rubrum S1H
Annotation: Bacteriochlorophyll/chlorophyll synthetase (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 62% identical to BCHG_RHOS4: Bacteriochlorophyll synthase 33 kDa chain (bchG) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
KEGG orthology group: K04040, chlorophyll synthase [EC: 2.5.1.62] (inferred from 100% identity to rru:Rru_A0627)MetaCyc: 74% identical to bacteriochlorophyll b synthase (Blastochloris viridis)
RXN-17480 [EC: 2.5.1.133]
Predicted SEED Role
"Chlorophyll a synthase ChlG (EC 2.5.1.62)" in subsystem Chlorophyll Biosynthesis (EC 2.5.1.62)
MetaCyc Pathways
- chlorophyll a biosynthesis II (4/5 steps found)
- chlorophyll a2 biosynthesis (1/1 steps found)
- chlorophyll a biosynthesis I (1/2 steps found)
- chlorophyll a biosynthesis III (1/2 steps found)
- chlorophyll b2 biosynthesis (1/4 steps found)
- bacteriochlorophyll b biosynthesis (3/7 steps found)
- chlorophyll cycle (3/7 steps found)
- superpathway of bacteriochlorophyll a biosynthesis (13/26 steps found)
- bacteriochlorophyll a biosynthesis (3/13 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.5.1.133 or 2.5.1.62
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RWR4 at UniProt or InterPro
Protein Sequence (303 amino acids)
>Rru_A0627 Bacteriochlorophyll/chlorophyll synthetase (NCBI) (Rhodospirillum rubrum S1H) MQRTAVLPYVQLLKPITWFAPMWAFGCGLISSGLPVWDRWPVIALGVLLCGPLVCGTSQA VNDWFDRHVDAINEPDRPIPSGRIPGRVGLYIAIGWTVLSLAVAWVLGPWVFGAAIFGLA LAWAYSAPPFRLKGNGWWGNSAVGLCYEGLPWFTGAAVIAGALPDTRIVLLAVLYSIGAH GIMTLNDFKAVEGDIRMGVRSLPVQLGVAPAARLACAVMAVPQMVVIGLVASWDRPYHAG AVGLLLLAQFVLMARLLKRPRELAPWYNATGTTLYVIGMMVSAFALAPLIGAVELAPLIG AAP