Protein Info for Rru_A0540 in Rhodospirillum rubrum S1H

Annotation: Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 PF00158: Sigma54_activat" amino acids 121 to 286 (166 residues), 239.5 bits, see alignment E=3.4e-75 PF14532: Sigma54_activ_2" amino acids 126 to 291 (166 residues), 70.8 bits, see alignment E=2.8e-23 PF07728: AAA_5" amino acids 144 to 264 (121 residues), 38 bits, see alignment E=3.2e-13 PF02954: HTH_8" amino acids 387 to 427 (41 residues), 56.4 bits, see alignment 4e-19

Best Hits

Swiss-Prot: 62% identical to FLBD_CAUVC: Transcriptional regulatory protein FlbD (flbD) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0540)

Predicted SEED Role

"Transcriptional regulatory protein flbD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RX01 at UniProt or InterPro

Protein Sequence (445 amino acids)

>Rru_A0540 Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) (Rhodospirillum rubrum S1H)
MRLLIVGSLDGQVGEASRMAMDRGAQVSQVGGIDQALAFLRDGKGADLVMIDVRLDVNRL
MVGMTEERMATPVVAYGVGTDTQAAVRAIKAGAREYIPLPPDPELIAAVLEAVTEESHAL
VYKDPAMGALVRMAEQIAPSDASVLIVGESGTGKEIIARHIHRKSRRAQGRFIAVNCAAI
PEALLESELFGHEKGAFTGAVARRLGKFEEANGGTLLLDEISEMDVRLQAKLLRVLQERE
IDRVGGRQPIKVDVRILATSNRDMEAEVRAGHFREDLFFRLNVITLALPPLRKRPADIDL
LADHFARKFADLNGVPYRPLADETRQSLRGHSWRGNVRELENTLHRAVLLSSGPRILPEA
ILLTGGDTANAPAGESTLTGSLVGRTVADVERDLIIDTLRHTLGNRTHAATILGISIRTL
RNKLKQYTEEGIPVPAPGEGEATHP