Protein Info for Rru_A0524 in Rhodospirillum rubrum S1H

Annotation: MCP methyltransferase, CheR-type (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 PF03705: CheR_N" amino acids 4 to 54 (51 residues), 41.5 bits, see alignment 8.4e-15 PF01739: CheR" amino acids 70 to 262 (193 residues), 193.4 bits, see alignment E=2.9e-61

Best Hits

Swiss-Prot: 34% identical to CHER_BACSU: Chemotaxis protein methyltransferase (cheR) from Bacillus subtilis (strain 168)

KEGG orthology group: K00575, chemotaxis protein methyltransferase CheR [EC: 2.1.1.80] (inferred from 100% identity to rru:Rru_A0524)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RX17 at UniProt or InterPro

Protein Sequence (280 amino acids)

>Rru_A0524 MCP methyltransferase, CheR-type (NCBI) (Rhodospirillum rubrum S1H)
MKPEDFDFISKLLKDKSGLVLTKDKSYLIESRLMPLARKRGFKGLDELIGQLRRRDLALE
REITEAMTTNESFFFRDSKPFDQFRQVVLPNILKARASKKSFRIWCAAASSGQEPYSLAM
ILKEEAARLAGWRVEIVGTDLSTDILKKARSGLYSQFEVQRGMPMNLLVKYFKKKDEMWE
IDAGIRAMVQYKEWNLLEDLRPLGQFDVVYCRNVLIYFDQPTKTKVLDAAAALMPEDGVL
YLGGAETVLGITNAFRPIPGQRGVYAVAKGENVKSLGAEA