Protein Info for Rru_A0506 in Rhodospirillum rubrum S1H
Annotation: Glycoside hydrolase (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00700, 1,4-alpha-glucan branching enzyme [EC: 2.4.1.18] (inferred from 100% identity to rru:Rru_A0506)Predicted SEED Role
"Malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141)" in subsystem Trehalose Biosynthesis (EC 3.2.1.141)
MetaCyc Pathways
- glycogen biosynthesis I (from ADP-D-Glucose) (4/4 steps found)
- trehalose biosynthesis V (2/3 steps found)
- starch biosynthesis (6/10 steps found)
- glycogen biosynthesis III (from α-maltose 1-phosphate) (4/8 steps found)
- glycogen biosynthesis II (from UDP-D-Glucose) (1/4 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.4.1.18, 3.2.1.141
Use Curated BLAST to search for 2.4.1.18 or 3.2.1.141
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RX35 at UniProt or InterPro
Protein Sequence (606 amino acids)
>Rru_A0506 Glycoside hydrolase (NCBI) (Rhodospirillum rubrum S1H) MTRRFGARVEGDGVRFSLWAPAAERVEVVIEGAAESRPVAMVPGGEGWFGAMVGGIGAGA LYRFRIDGADLVPDPASRFQPRDVGGPSQVVDASGYAWKTDGWKGRPWAETVLYELHLGT FSRKGTYEGARARLGDLVDLGVSAIELMPLADFVGQRNWGYDGVLPFAPDSVYGTPEQLK ALIDAAHGLGLMVFLDVVYNHFGPEGNWLGRYAPSFFTQAHQTPWGAAIDFERPEVRDFF VANALQWLEEYRFDGLRFDAVHAILDAEERHILGEIAVAVREALPADRHVHLVLENDANE ARRLIGGTDVVAVRGRYDAQWNDDIHHAFHVVATGETGGYYADYAAQPLAHLGRCLAEGF AYQGESSAHRGGMARGEPTTALPPTAFVAFLQNHDQIGNRALGERLSTLAAPDRLRALRT ILLLGPQIPMLFMGEEWSSSRPFLFFCDFHGDLAEAVREGRRREFAAFPQFSTPETRDRI PDPNAPETARACVLDWSERDQPTGAAVLAHHKHLLELRFAKIVPLLGRLRPGGGRCERIG EGGLAVRWGIDDGRDLLMLAQLAEAGSLPGAPPQADLIYRSDGGERAEAPLGPWSVLFAL VPETSR