Protein Info for Rru_A0427 in Rhodospirillum rubrum S1H

Annotation: Short-chain dehydrogenase/reductase SDR (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 223 to 243 (21 residues), see Phobius details PF08659: KR" amino acids 6 to 158 (153 residues), 38.9 bits, see alignment E=1.4e-13 PF00106: adh_short" amino acids 6 to 191 (186 residues), 139.6 bits, see alignment E=1.4e-44 PF13561: adh_short_C2" amino acids 11 to 194 (184 residues), 79.4 bits, see alignment E=4.8e-26

Best Hits

Swiss-Prot: 43% identical to Y5909_MYXXD: Uncharacterized oxidoreductase MXAN_5909 (MXAN_5909) from Myxococcus xanthus (strain DK 1622)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0427)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RXB3 at UniProt or InterPro

Protein Sequence (256 amino acids)

>Rru_A0427 Short-chain dehydrogenase/reductase SDR (NCBI) (Rhodospirillum rubrum S1H)
MKSPRTILITGASSGLGAALARGYARPGRRLVLGARRAEALAAIAQDCRAAGAIVETALV
DVTDRAATAAWVIAADEAGALDLVIANAGISGGTGGGGEAAEQTRALFAVNVDGLFNTLL
PIIPRFRARKRGQIAVMASLASFRGTPGAPAYCASKAAVKVWGEGMRGVLADDGVELSVI
CPGFVRTPMTAVNEFPMPFLMEADKAARLIARRLEANAGRIAFPWPMAFGAWMIAALPEA
LAGRLLARTPRKPAGF