Protein Info for Rru_A0410 in Rhodospirillum rubrum S1H

Annotation: DnaB helicase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 507 TIGR00665: replicative DNA helicase" amino acids 23 to 499 (477 residues), 519.8 bits, see alignment E=2.7e-160 PF00772: DnaB" amino acids 24 to 125 (102 residues), 101.3 bits, see alignment E=4.4e-33 PF03796: DnaB_C" amino acids 202 to 497 (296 residues), 340.5 bits, see alignment E=8.7e-106 PF13481: AAA_25" amino acids 218 to 395 (178 residues), 48.3 bits, see alignment E=1.5e-16

Best Hits

KEGG orthology group: K02314, replicative DNA helicase [EC: 3.6.4.12] (inferred from 100% identity to rru:Rru_A0410)

Predicted SEED Role

"Replicative DNA helicase (EC 3.6.1.-)" in subsystem DNA-replication (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-, 3.6.4.12

Use Curated BLAST to search for 3.6.1.- or 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RXD0 at UniProt or InterPro

Protein Sequence (507 amino acids)

>Rru_A0410 DnaB helicase (NCBI) (Rhodospirillum rubrum S1H)
MTGHFLAAQNDPSAGPAAEATRLPPANIEAEQALLGAILTNNRVLEKVGDFLRPAHFSHP
AHGAIYEACVTLTERGHLANPVTLAPYLDHRTELEEVGGARYLAQLVNAVVTIINAEDYG
TLVHDLFLRRELIALGSDLVNDAFEADLDSSAVDQIEGAERKLFDLATTGQTEGGLKSFK
DSLIGAIDMAEKAHKREGQLAGVPSLLVDLDKKLGGLHDSDLLILAGRPSMGKTALATTI
AFNAATFFRQEAQAGEPSKAVAFFSLEMSAEQLATRILSERAEVSSHRLRTGELANEDFD
RVLQVATQLHSIPLFIDDTPALSVGAMRTRCRRLARSHGGGGNGLGLIVVDYLQLLQGGK
GERSENRVQEVSAITRGLKALAKELNVPVMALSQLSRQVESRDDKRPQLSDLRESGSIEQ
DADVVMFVFREQYYLERAEPLRKPDETDDRYQERHLSWIKRCEDAYNKAEVIIAKQRHGP
IGSVSLFFDGNYTRFGNLQGGEPPPDL