Protein Info for Rru_A0366 in Rhodospirillum rubrum S1H

Annotation: Polynucleotide adenylyltransferase region (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 PF01743: PolyA_pol" amino acids 96 to 221 (126 residues), 99.6 bits, see alignment E=1.7e-32 PF12627: PolyA_pol_RNAbd" amino acids 253 to 308 (56 residues), 33.9 bits, see alignment 2.2e-12

Best Hits

KEGG orthology group: K00970, poly(A) polymerase [EC: 2.7.7.19] (inferred from 100% identity to rru:Rru_A0366)

Predicted SEED Role

"tRNA nucleotidyltransferase (EC 2.7.7.21) (EC 2.7.7.25)" in subsystem Polyadenylation bacterial or tRNA nucleotidyltransferase (EC 2.7.7.21, EC 2.7.7.25)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.19 or 2.7.7.21 or 2.7.7.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RXH4 at UniProt or InterPro

Protein Sequence (525 amino acids)

>Rru_A0366 Polynucleotide adenylyltransferase region (NCBI) (Rhodospirillum rubrum S1H)
MPVRATRRERSILPSAPPFPANPRQRRRQPLRRPLLPKATQDMDPRLPIEGRPDRHLGAM
LAGERPPVGQLGPLDWLVDPRTVAVMTALTAEGGEARFVGGCVRDSLLRRDPLRPMDIDI
ATTERPERVIALIEAAGLKAVPTGLAHGTLTVVAGGKPFEVTTLRRDTACDGRHAEVAFT
TSFREDAGRRDFTINALSADREGRVFDYFDGISDLHAGWVRFIGRPMDRIAEDYLRILRF
FRFHARFGRPPADPDALSACAAQAAGLDRLSAERVRSELLKILDTADPAGVLMAMRGVHV
LERVLPEAGDVTNLRMLTLLETRGLMLPGLGADPLRRLACVVGPPALSAGSGPPALSAVA
GSDPSRDSGAALGARLRLSRAETARLTGMLDAPAGRWPDPDAGEGALRRLLDGEGKDLVI
DRALLRWAAERGKGPYPRAERTARWRALIETALGWTAPTFPLGGRDALACGLKGPAVGEA
LAALRGRWLEGGCQAGRDEMLAWLATWRDGAADEPPAPIKGVEPL