Protein Info for Rru_A0144 in Rhodospirillum rubrum S1H

Annotation: NADH:flavin oxidoreductase/NADH oxidase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 PF00724: Oxidored_FMN" amino acids 5 to 340 (336 residues), 227.1 bits, see alignment E=1.9e-71

Best Hits

Swiss-Prot: 48% identical to NAMA_GEOTN: NADPH dehydrogenase (namA) from Geobacillus thermodenitrificans (strain NG80-2)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0144)

Predicted SEED Role

"NADH-dependent flavin oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RY46 at UniProt or InterPro

Protein Sequence (367 amino acids)

>Rru_A0144 NADH:flavin oxidoreductase/NADH oxidase (NCBI) (Rhodospirillum rubrum S1H)
MATSQLFQPITLDGLTLPNRIIIAPMCQYSAKDGRTTGWHTIHLGQLALSGAGMLIIEAT
AVEPAGRISPADLGLWSDETEHALAETLAQVRAYSTMPIALQIAHAGRKASTAVPWEGGA
QIAPDAGGWQTRAPSALPFDPSENPPVALTVADLTELREAFADTARRAARAGIDAIEIHA
AHGYLLHEFLSPLSNRRSDAYGGSLENRLRFPLEVFDAVRAAFPAGKPVGVRVSATDWVE
GGWSLEETIALAEALKARGCAFIHVSSGALSLDQKIPVGPGYQVPLARAIKAATGLPTIA
VGLITEPEQAETILVSGDADMIGLARGILYDPRWPWHAAARLGQKIEAAPQYLRAAPHQA
ADLFKVV