Protein Info for Rru_A0136 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF6, transmembrane (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 41 to 62 (22 residues), see Phobius details amino acids 73 to 95 (23 residues), see Phobius details amino acids 101 to 123 (23 residues), see Phobius details amino acids 132 to 151 (20 residues), see Phobius details amino acids 161 to 182 (22 residues), see Phobius details amino acids 194 to 213 (20 residues), see Phobius details amino acids 225 to 246 (22 residues), see Phobius details amino acids 256 to 275 (20 residues), see Phobius details amino acids 281 to 299 (19 residues), see Phobius details PF00892: EamA" amino acids 20 to 146 (127 residues), 50.8 bits, see alignment E=9.8e-18 amino acids 165 to 298 (134 residues), 45.9 bits, see alignment E=3.3e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0136)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RY54 at UniProt or InterPro

Protein Sequence (308 amino acids)

>Rru_A0136 Protein of unknown function DUF6, transmembrane (NCBI) (Rhodospirillum rubrum S1H)
MTAAPSPSASLSLRVAPAVFVLLWSTGFIGARLVLPHAEPLTVLCLRFAATVALLGPLCL
VLKARWPTSPHQLLHVAVAGILVHALYLGGVFAAISLGMPAGLTALVVGIQPLLTAALAG
PVLGEKTTARQGLGLVLGLAGVAAVLGDKLAPQAGTLFDGFGAAAMICALAALCGITFGT
LYQKRFCQGVDLTSGSLIQFIVSGVVLLPFAYTFETMRVDWTAEFIFGLAWLVVGLSVGA
VTLLLAMIRHGAAGRVASLFYLVPPTTALMAWGLFDERLGPLALAGMAVTVAGVALVVAP
RRQTLAQR