Protein Info for Rru_A0085 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate cyclase (GGDEF domain) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 PF00072: Response_reg" amino acids 145 to 253 (109 residues), 71 bits, see alignment E=1.4e-23 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 269 to 433 (165 residues), 153 bits, see alignment E=3e-49 PF00990: GGDEF" amino acids 273 to 429 (157 residues), 128.1 bits, see alignment E=4.3e-41

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0085)

Predicted SEED Role

"Response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RYA5 at UniProt or InterPro

Protein Sequence (453 amino acids)

>Rru_A0085 Putative diguanylate cyclase (GGDEF domain) (NCBI) (Rhodospirillum rubrum S1H)
MDLLTGSDADIEIEEAPPGKILIVEDSPFFMHVLRRRIGQELGVPIIEAETLAQAALIIE
EEGSNLFLCLIDLVLPDAPNGEIVDYVTGKGLAAVVFTGAFSEEMREHVLSSAIIDYVTK
DSLASLDYLVAIVRRLCRNAHQKAIVVDDSRTARAYIGDLLRLYRFNVIEAVDGEEALAL
LAANPDIRLMVTDYYMPRIDGFELIKRVRQTHSRSALAIIGVSTGGSAPLSARFIKYGAN
DFINKPFLREEFFCRIAQNMDTLDYIAALARSAQIDPLTGLPNRRYLFDVASRALAATLR
VGGHPVVAMIDADHFKEINDRFGHDVGDQVLEALARVMDDHVQRKSDVLARFGGEEFCVF
VSDMSPEQAFTFFDGLRAAVAQSPLSVPGLDDLSLTISIGVSTCAAPDLRTMIHSADRLL
YDAKAAGRDCTVVEGLGERTQSCRQSSGKDEDA