Protein Info for Rru_A0038 in Rhodospirillum rubrum S1H

Annotation: Cytochrome c-type biogenesis protein CcmC (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 239 transmembrane" amino acids 17 to 40 (24 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details PF01578: Cytochrom_C_asm" amino acids 6 to 180 (175 residues), 140.2 bits, see alignment E=3.8e-45 TIGR01191: heme exporter protein CcmC" amino acids 41 to 222 (182 residues), 270.5 bits, see alignment E=3.9e-85

Best Hits

Swiss-Prot: 59% identical to CCMC_BRADU: Heme exporter protein C (cycZ) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K02195, heme exporter protein C (inferred from 100% identity to rru:Rru_A0038)

MetaCyc: 50% identical to cytochrome c maturation protein C (Escherichia coli K-12 substr. MG1655)
RXN-21407

Predicted SEED Role

"Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE" in subsystem Biogenesis of c-type cytochromes

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RYF2 at UniProt or InterPro

Protein Sequence (239 amino acids)

>Rru_A0038 Cytochrome c-type biogenesis protein CcmC (NCBI) (Rhodospirillum rubrum S1H)
MQKFANPTRFLKLSKVLVPWCAGLTAVLSVVGLVWGLAFAPPDYQQGETVRIMYVHVPSA
WMGMFAYMFMAAASAVALIWKHPLADLAARAAAPIGAAFTLICLVSGSLWGKPMWGAWWV
WDARLTSMLVLFFLYLGYMALANAFDDVTRGNRAAAILCLIGAVNVPIIKFSVDWWNTLH
QPASVVKMGGPAIDPSILWPLLLMGVAFQLYFATVVLLRMESGIAAAKVRALGLLEAGG