Protein Info for Rru_A0020 in Rhodospirillum rubrum S1H

Annotation: Glutathione peroxidase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00255: GSHPx
  • amino acids 4 to 111 (108 residues), 149 bits, E=1.7e-48

Best Hits

Swiss-Prot: 56% identical to GPX1_SYNY3: Hydroperoxy fatty acid reductase gpx1 (gpx1) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K00432, glutathione peroxidase [EC: 1.11.1.9] (inferred from 100% identity to rru:Rru_A0020)

MetaCyc: 56% identical to hydroperoxy fatty acid reductase 1 (Synechocystis sp. PCC 6803)
RXN-13944 [EC: 1.11.1.22]; 1.11.1.- [EC: 1.11.1.22]

Predicted SEED Role

"Glutathione peroxidase family protein"

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• glutathione-peroxide redox reactions (2/3 steps found)

KEGG Metabolic Maps

• Arachidonic acid metabolism
• Glutathione metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.9

Use Curated BLAST to search for 1.11.1.22 or 1.11.1.9

Sequence Analysis Tools

See Q2RYH0 at UniProt or InterPro

Protein Sequence (168 amino acids)

>Rru_A0020 Glutathione peroxidase (NCBI) (Rhodospirillum rubrum S1H)
MSPLYDIEVTTLDGAPQTLADYAGKVLLIVNVASKCGFTPQYKGLEALQRRYRDRGFCVL
GFPCNQFGHQEPGDAGEIKSFCTLTYDVSFPMFAKIDVNGPDAHPLYRLLKAEAKGLLGS
EAIKWNFTKFLVSADGETISRFAPTDTPESLRARIEALLPAAQGPLGA