Negative cofitness for SMa2143 from Sinorhizobium meliloti 1021

5,10-methylenetetrahydrofolate reductase
SEED: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
KEGG: methylenetetrahydrofolate reductase (NADPH)

Computing cofitness values with 243 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	SM_b20942		UDP glucose 4-epimerase	-0.43
2	SM_b20804		hypothetical protein	-0.42
3	SMa1459		Dehydrogenase, malate/L-lactate family	-0.40
4	SM_b20803		3-deoxy-manno-octulosonate cytidylyltransferase	-0.40
5	SMc04399		acyl-COA transferase	-0.39
6	SM_b20808		hypothetical protein	-0.39
7	SMc01361		dihydroorotase	-0.39
8	SM_b20562		hypothetical protein	-0.39
9	SMa0293		hypothetical protein	-0.38
10	SM_b20422		oxidoreductase	-0.38
11	SM_b20805		glycosyltransferase	-0.38
12	SMc01655		ABC transporter permease	-0.37
13	SMa0093		Branched-chain amino acid aminotransferase	-0.37
14	SM_b21113		hypothetical protein	-0.37
15	SMc04396		periplasmic binding protein	-0.37
16	SMc04095		acyl-COA synthetase	-0.36
17	SM_b20380		ABC transporter ATP-binding protein	-0.36
18	SMc01360		aspartate carbamoyltransferase catalytic subunit	-0.36
19	SMc03979		glyceraldehyde-3-phosphate dehydrogenase	-0.36
20	SM_b21175		phosphate uptake ABC transporter permease	-0.35

Or look for positive cofitness