Negative cofitness for SMa1789 from Sinorhizobium meliloti 1021

CyaI4 adenylate/guanylate cyclase
SEED: Adenylate cyclase (EC 4.6.1.1) / Guanylate cyclase (EC 4.6.1.2)

Computing cofitness values with 243 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	SMc02071		hydrolase glycosidase	-0.46
2	SMc03864		amino acid-binding periplasmic (signal peptide) ABC transporter protein	-0.41
3	SM_b20446		mannonate dehydratase	-0.40
4	SMc02484		amino acid efflux transmembrane protein	-0.38
5	SMa1821		hydrolase	-0.38
6	SMc00675		hypothetical protein	-0.38
7	SMc02149		hypothetical protein	-0.38
8	SM_b20805		glycosyltransferase	-0.38
9	SMc02140		phosphate regulon transcriptional regulatory protein	-0.37
10	SM_b20821		ATPGTP-binding hydroxymethyltransferase	-0.37
11	SMc03139		hypothetical protein	-0.37
12	SM_b21184		acetate kinase	-0.37
13	SMc03773		hypothetical protein	-0.37
14	SM_b21151		substrate-binding protein of a sugar uptake ABC transporter system	-0.37
15	SM_b20532		hypothetical protein	-0.36
16	SM_b21134		amino acid processing enzyme, low specificity D-threonine aldolase	-0.36
17	SMc01457		transport transmembrane protein	-0.36
18	SMc02114		hypothetical protein	-0.36
19	SMc03870		thiamine transporter membrane protein	-0.36
20	SMc01700		peptidyl-prolyl cis-trans isomerase A	-0.36

Or look for positive cofitness