Negative cofitness for SMa1591 from Sinorhizobium meliloti 1021

CyaI3 adenylate/guanylate cyclase
SEED: Adenylate cyclase (EC 4.6.1.1) / Guanylate cyclase (EC 4.6.1.2)

Computing cofitness values with 243 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	SMa0293		hypothetical protein	-0.43
2	SMc04399		acyl-COA transferase	-0.41
3	SMc02758		nucleotidyl transferase	-0.40
4	SMa1850		oxidoreductase	-0.38
5	SM_b21113		hypothetical protein	-0.38
6	SMc02486		oxidoreductase	-0.38
7	SMc01430		acetolactate synthase 3 regulatory subunit	-0.38
8	SMa1370		ABC transporter ATP-binding protein	-0.37
9	SMc00494		phosphoribosylformylglycinamidine synthase subunit PurS	-0.37
10	SMc00726		thiol:disulfide interchange redox-active center transmembrane protein	-0.37
11	SMc02899		prephenate dehydratase	-0.36
12	SMc00615		phosphoribosylaminoimidazole synthetase	-0.36
13	SMc03112		B12-dependent methionine synthase	-0.36
14	SMc03979		glyceraldehyde-3-phosphate dehydrogenase	-0.36
15	SMc00137		hypothetical protein	-0.36
16	SMc03993		hypothetical protein	-0.35
17	SMc03797		homoserine O-succinyltransferase	-0.35
18	SMa0934		TraA1 conjugal transfer protein	-0.35
19	SMc03121		periplasmic binding ABC transporter protein	-0.35
20	SMc02717		2-isopropylmalate synthase	-0.35

Or look for positive cofitness