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  • Negative cofitness for SMa1318 from Sinorhizobium meliloti 1021

    VirB3 type IV secretion protein
    SEED: Inner membrane protein forms channel for type IV secretion of T-DNA complex (VirB3)
    KEGG: type IV secretion system protein VirB3

    Computing cofitness values with 243 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 SMc01880 pantoate--beta-alanine ligase -0.43
    2 SMc01881 3-methyl-2-oxobutanoate hydroxymethyltransferase -0.42
    3 SMc02124 nitrite reductase -0.40
    4 SMc00092 phosphoadenosine phosphosulfate reductase -0.40
    5 SMc00090 sulfate adenylyltransferase -0.40
    6 SMc03776 gamma-glutamyl kinase -0.39
    7 SMc01053 siroheme synthase -0.39
    8 SMc02123 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) -0.39
    9 SMc01054 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) -0.39
    10 SMc00640 phosphoserine aminotransferase -0.39
    11 SMc00091 sulfate adenylyltransferase -0.39
    12 SMc02899 prephenate dehydratase -0.39
    13 SMc02217 O-succinylhomoserine sulfhydrylase -0.39
    14 SMc03797 homoserine O-succinyltransferase -0.38
    15 SMc03980 hypothetical protein -0.38
    16 SMc03823 isopropylmalate isomerase large subunit -0.38
    17 SMc00614 phosphoribosylglycinamide formyltransferase -0.38
    18 SMc01494 phosphoserine phosphatase -0.38
    19 SMc00641 D-3-phosphoglycerate dehydrogenase -0.38
    20 SMc04405 3-isopropylmalate dehydrogenase -0.38

    Or look for positive cofitness