Negative cofitness for SM_b21052 from Sinorhizobium meliloti 1021

epimerase dehydratase
SEED: dTDP-glucose 4,6-dehydratase (EC 4.2.1.46)

Computing cofitness values with 243 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	SMc01770		serine hydroxymethyltransferase	-0.49
2	SMc03978		transketolase	-0.49
3	SM_b21113		hypothetical protein	-0.48
4	SMc03229		NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	-0.48
5	SMc02899		prephenate dehydratase	-0.46
6	SMc03112		B12-dependent methionine synthase	-0.46
7	SMc03823		isopropylmalate isomerase large subunit	-0.46
8	SMc02217		O-succinylhomoserine sulfhydrylase	-0.45
9	SMc00488		phosphoribosylformylglycinamidine synthase II	-0.45
10	SMc00615		phosphoribosylaminoimidazole synthetase	-0.45
11	SMc04405		3-isopropylmalate dehydrogenase	-0.45
12	SMc02717		2-isopropylmalate synthase	-0.45
13	SMc03797		homoserine O-succinyltransferase	-0.45
14	SMc00640		phosphoserine aminotransferase	-0.45
15	SMc00993		phosphoribosylamine--glycine ligase	-0.44
16	SMc04045		dihydroxy-acid dehydratase	-0.44
17	SMc03777		gamma-glutamyl phosphate reductase	-0.44
18	SMa0933		TraC conjugal transfer protein	-0.44
19	SMc00494		phosphoribosylformylglycinamidine synthase subunit PurS	-0.44
20	SMc01361		dihydroorotase	-0.44

Or look for positive cofitness