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  • Negative cofitness for SM_b20186 from Sinorhizobium meliloti 1021

    glutathione-dependent formaldehyde-activating protein
    SEED: Glutathione-dependent formaldehyde-activating enzyme (EC 4.4.1.22)
    KEGG: S-(hydroxymethyl)glutathione synthase

    Computing cofitness values with 243 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 SMa1435 ABC transporter permease -0.35
    2 SMc04146 phosphoketolase -0.34
    3 SMa2079 ABC transporter ATP-binding protein -0.32
    4 SMc00518 hypothetical protein -0.30
    5 SMc02356 branched chain amino acid ABC transporter periplasmic protein -0.30
    6 SMc02986 hypothetical protein -0.29
    7 SMc00414 hypothetical protein -0.29
    8 SMc02124 nitrite reductase -0.29
    9 SMc01610 transcriptional regulator -0.28
    10 SMa1296 alcohol dehydrogenase -0.28
    11 SMc00090 sulfate adenylyltransferase -0.28
    12 SMa0709 ABC transporter substrate-binding protein -0.28
    13 SM_b21320 bifunctional glycosyltransferase -0.28
    14 SMc01770 serine hydroxymethyltransferase -0.28
    15 SMc00614 phosphoribosylglycinamide formyltransferase -0.28
    16 SMc03777 gamma-glutamyl phosphate reductase -0.27
    17 SMc02344 periplasmic binding protein -0.27
    18 SMc00092 phosphoadenosine phosphosulfate reductase -0.27
    19 SMc01053 siroheme synthase -0.27
    20 SMc02123 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) -0.27

    Or look for positive cofitness