Negative cofitness for Rv3744 from Mycobacterium tuberculosis H37Rv

Metal sensor transcriptional regulator (ArsR-SmtB family)
SEED: Cobalt(II) binding transcription repressor, nmtR

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Rv1819c		Probable drug-transport transmembrane ATP-binding protein ABC transporter BacA	-0.37
2	Rv0187		Probable O-methyltransferase	-0.31
3	Rv0823c		Possible transcriptional regulatory protein	-0.30
4	Rv2848c		Probable cobyrinic acid A,C-diamide synthase CobB	-0.27
5	Rv1925		Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase)	-0.27
6	Rv1439c		Unknown protein	-0.27
7	Rv2344c		Probable deoxyguanosine triphosphate triphosphohydrolase Dgt (dGTPase) (dGTP triphosphohydrolase)	-0.26
8	Rv0295c		Conserved protein	-0.25
9	Rv3815c		Possible acyltransferase	-0.25
10	Rv0533c		3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III)	-0.25
11	Rv1215c		Conserved protein	-0.23
12	Rv1324		Possible thioredoxin	-0.23
13	Rv0963c		Conserved hypothetical protein	-0.23
14	Rv0394c		Possible secreted protein	-0.23
15	Rv0577		Conserved protein TB27.3	-0.23
16	Rv3203		Possible lipase LipV	-0.23
17	Rv2118c		RNA methyltransferase	-0.22
18	Rv0212c		Possible transcriptional regulatory protein NadR (probably AsnC-family)	-0.22
19	Rv1077		Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450)	-0.22
20	Rv3337		Conserved hypothetical protein	-0.22

Or look for positive cofitness