Negative cofitness for Rv3592 from Mycobacterium tuberculosis H37Rv

Possible heme degrading protein MhuD
SEED: Antibiotic biosynthesis monooxygenase

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv2880c Conserved hypothetical protein -0.31
2 Rv2606c Possible pyridoxine biosynthesis protein SnzP -0.31
3 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) -0.30
4 Rv3229c Possible linoleoyl-CoA desaturase (delta(6)-desaturase) -0.30
5 Rv3340 Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetylhomoserine (thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase) -0.30
6 Rv1523 Probable methyltransferase -0.30
7 Rv3690 Probable conserved membrane protein -0.29
8 Rv1272c Probable drugs-transport transmembrane ATP-binding protein ABC transporter -0.28
9 Rv3131 Conserved protein -0.28
10 Rv0634A Unknown protein -0.28
11 Rv1824 Conserved hypothetical membrane protein -0.27
12 Rv1568 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA -0.27
13 Rv0483 Probable conserved lipoprotein LprQ -0.27
14 Rv0096 PPE family protein PPE1 -0.26
15 Rv3803c Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C) -0.26
16 Rv2556c Conserved hypothetical protein -0.26
17 Rv2038c Probable sugar-transport ATP-binding protein ABC transporter -0.26
18 Rv0035 Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) -0.25
19 Rv1882c Probable short-chain type dehydrogenase/reductase -0.24
20 Rv3230c Hypothetical oxidoreductase -0.24

Or look for positive cofitness