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  • Negative cofitness for Rv3485c from Mycobacterium tuberculosis H37Rv

    Probable short-chain type dehydrogenase/reductase
    SEED: Short-chain dehydrogenase/reductase SDR

    Computing cofitness values with 236 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 Rv3347c PPE family protein PPE55 -0.32
    2 Rv2891 Conserved hypothetical protein -0.31
    3 Rv2500c Possible acyl-CoA dehydrogenase FadE19 (MMGC) -0.31
    4 Rv0036c Conserved protein -0.31
    5 Rv3382c Probable LYTB-related protein LytB1 -0.30
    6 Rv1681 Possible molybdopterin biosynthesis protein MoeX -0.30
    7 Rv3343c PPE family protein PPE54 -0.30
    8 Rv0043c Probable transcriptional regulatory protein (probably GntR-family) -0.30
    9 Rv1905c Probable D-amino acid oxidase Aao -0.29
    10 Rv2762c Conserved hypothetical protein -0.29
    11 Rv3345c PE-PGRS family protein PE_PGRS50 -0.29
    12 Rv1069c Conserved protein -0.29
    13 Rv3319 Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase) -0.28
    14 Rv3508 PE-PGRS family protein PE_PGRS54 -0.28
    15 Rv1068c PE-PGRS family protein PE_PGRS20 -0.28
    16 Rv2161c Conserved protein -0.27
    17 Rv0279c PE-PGRS family protein PE_PGRS4 -0.27
    18 Rv0278c PE-PGRS family protein PE_PGRS3 -0.27
    19 Rv1592c Conserved hypothetical protein -0.27
    20 Rv2143 Conserved hypothetical protein -0.27

    Or look for positive cofitness