Negative cofitness for Rv3133c from Mycobacterium tuberculosis H37Rv

Two component transcriptional regulatory protein DevR (probably LuxR/UhpA-family)
SEED: Two component transcriptional regulatory protein DevR
KEGG: two-component system, NarL family, response regulator DevR

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv2299c Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) -0.28
2 Rv1114 Possible toxin VapC32. Contains PIN domain. -0.26
3 Rv3903c Hypothetical alanine and proline rich protein -0.26
4 Rv3153 Probable NADH dehydrogenase I (chain I) NuoI (NADH-ubiquinone oxidoreductase chain I) -0.26
5 Rv0456B Possible antitoxin MazE1 -0.26
6 Rv1780 Conserved protein -0.25
7 Rv1266c Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H) -0.25
8 Rv2503c Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (beta subunit) ScoB (3-oxo-acid:CoA transferase) (OXCT B) (succinyl CoA:3-oxoacid CoA-transferase) -0.24
9 Rv0851c Probable short-chain type dehydrogenase/reductase -0.24
10 Rv1926c Immunogenic protein Mpt63 (antigen Mpt63/MPB63) (16 kDa immunoprotective extracellular protein) -0.24
11 Rv0051 Probable conserved transmembrane protein -0.24
12 Rv2444c Possible ribonuclease E Rne -0.24
13 Rv2203 Possible conserved membrane protein -0.23
14 Rv1869c Probable reductase -0.23
15 Rv0133 GCN5-related N-acetyltransferase -0.23
16 Rv1160 Probable mutator protein MutT2 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) -0.23
17 Rv0491 Two component sensory transduction protein RegX3 (transcriptional regulatory protein) (probably LuxR-family) -0.23
18 Rv3164c Probable methanol dehydrogenase transcriptional regulatory protein MoxR3 -0.23
19 Rv2807 Conserved hypothetical protein -0.22
20 Rv0623 Possible antitoxin VapB30 -0.22

Or look for positive cofitness