Negative cofitness for Rv2761c from Mycobacterium tuberculosis H37Rv

Possible type I restriction/modification system specificity determinant HsdS (S protein)
SEED: Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Rv3469c		Probable 4-hydroxy-2-oxovalerate aldolase MhpE (HOA)	-0.23
2	Rv3479		Possible transmembrane protein	-0.22
3	Rv2387		Conserved protein	-0.22
4	Rv0446c		Possible conserved transmembrane protein	-0.21
5	Rv0583c		Probable conserved lipoprotein LpqN	-0.21
6	Rv0926c		Conserved hypothetical protein	-0.21
7	Rv3887c		ESX conserved component EccD2. ESX-2 type VII secretion system protein. Probable transmembrane protein.	-0.20
8	Rv2031c		Heat shock protein HspX (alpha-crystallin homolog) (14 kDa antigen) (HSP16.3)	-0.20
9	Rv0938		ATP dependent DNA ligase LigD (ATP dependent polydeoxyribonucleotide synthase) (thermostable DNA ligase) (ATP dependent polynucleotide ligase) (sealase) (DNA repair enzyme) (DNA joinase)	-0.20
10	Rv2123		PPE family protein PPE37	-0.20
11	Rv0868c		Probable molybdenum cofactor biosynthesis protein D 2 MoaD2 (molybdopterin converting factor small subunit) (molybdopterin [MPT] converting factor, subunit 1)	-0.20
12	Rv1836c		Conserved protein	-0.20
13	Rv1355c		Possible molybdopterin biosynthesis protein MoeY	-0.19
14	Rv0101		Probable peptide synthetase Nrp (peptide synthase)	-0.19
15	Rv1909c		Ferric uptake regulation protein FurA (fur)	-0.19
16	Rv1522c		Probable conserved transmembrane transport protein MmpL12	-0.19
17	Rv0953c		Possible oxidoreductase	-0.19
18	Rv0686		Probable membrane protein	-0.18
19	Rv0904c		Putative acetyl-coenzyme A carboxylase carboxyl transferase (subunit beta) AccD3 (accase beta chain)	-0.18
20	Rv1936		Possible monooxygenase	-0.18

Or look for positive cofitness