Negative cofitness for Rv2435c from Mycobacterium tuberculosis H37Rv

Probable cyclase (adenylyl-or guanylyl-)(adenylate-or guanylate-)
SEED: Adenylate cyclase (EC 4.6.1.1)
KEGG: putative cyclase

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Rv0897c		Probable oxidoreductase	-0.27
2	Rv2046		Probable lipoprotein LppI	-0.27
3	Rv2323c		Conserved protein	-0.27
4	Rv2792c		Possible resolvase	-0.25
5	Rv2116		Conserved lipoprotein LppK	-0.24
6	Rv1031		Probable potassium-transporting ATPase C chain KdpC (potassium-translocating ATPase C chain) (ATP phosphohydrolase [potassium-transporting] C chain) (potassium binding and translocating subunit C)	-0.24
7	Rv1228		Probable lipoprotein LpqX	-0.23
8	Rv3854c		Monooxygenase EthA	-0.23
9	Rv2579		Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase)	-0.23
10	Rv2724c		Probable acyl-CoA dehydrogenase FadE20	-0.23
11	Rv3511		PE-PGRS family protein PE_PGRS55	-0.23
12	Rv3083		Probable monooxygenase (hydroxylase)	-0.23
13	Rv1111c		Conserved hypothetical protein	-0.23
14	Rv2492		Hypothetical protein	-0.23
15	Rv0475		Iron-regulated heparin binding hemagglutinin HbhA (adhesin)	-0.23
16	Rv0306		Putative oxidoreductase	-0.23
17	Rv3515c		Fatty-acid-CoA ligase FadD19 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	-0.23
18	Rv1910c		Probable exported protein	-0.22
19	Rv0047c		Conserved protein	-0.22
20	Rv1076		Possible lipase LipU	-0.22

Or look for positive cofitness