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  • Negative cofitness for Rv2101 from Mycobacterium tuberculosis H37Rv

    Probable helicase HelZ
    SEED: Helicase, SNF2/RAD54 family

    Computing cofitness values with 236 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 Rv3201c Probable ATP-dependent DNA helicase -0.68
    2 Rv2095c Proteasome accessory factor C PafC -0.66
    3 Rv3364c Conserved protein -0.62
    4 Rv3202c Possible ATP-dependent DNA helicase -0.62
    5 Rv2737c RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. -0.60
    6 Rv3585 DNA repair protein RadA (DNA repair protein SMS) -0.57
    7 Rv2096c Proteasome accessory factor B PafB -0.57
    8 Rv0003 DNA replication and repair protein RecF (single-strand DNA binding protein) -0.56
    9 Rv1020 Probable transcription-repair coupling factor Mfd (TRCF) -0.51
    10 Rv3365c Conserved protein -0.50
    11 Rv1634 Possible drug efflux membrane protein -0.47
    12 Rv3272 Conserved hypothetical protein -0.46
    13 Rv3273 Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) -0.46
    14 Rv1109c Conserved protein -0.44
    15 Rv1108c Probable exodeoxyribonuclease VII (large subunit) XseA (exonuclease VII large subunit) -0.40
    16 Rv1277 Conserved hypothetical protein -0.37
    17 Rv0474 Probable transcriptional regulatory protein -0.35
    18 Rv1278 Hypothetical protein -0.35
    19 Rv0767c Conserved hypothetical protein -0.34
    20 Rv2340c PE-PGRS family protein PE_PGRS39 -0.31

    Or look for positive cofitness