Negative cofitness for Rv1730c from Mycobacterium tuberculosis H37Rv

Possible penicillin-binding protein
SEED: Beta-lactamase (EC 3.5.2.6)

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv0089 Possible methyltransferase/methylase -0.35
2 Rv3397c Probable phytoene synthase PhyA -0.32
3 Rv1815 Conserved protein -0.32
4 Rv0491 Two component sensory transduction protein RegX3 (transcriptional regulatory protein) (probably LuxR-family) -0.31
5 Rv3138 Probable pyruvate formate lyase activating protein PflA (formate acetyltransferase activating enzyme) ([pyruvate formate-lyase] activating enzyme) -0.31
6 Rv1020 Probable transcription-repair coupling factor Mfd (TRCF) -0.30
7 Rv2270 Probable lipoprotein LppN -0.30
8 Rv1914c Unknown protein -0.30
9 Rv3395A Probable membrane protein -0.30
10 Rv3445c ESAT-6 like protein EsxU -0.30
11 Rv1450c PE-PGRS family protein PE_PGRS27 -0.29
12 Rv1278 Hypothetical protein -0.29
13 Rv0071 Possible maturase -0.29
14 Rv0881 Possible rRNA methyltransferase (rRNA methylase) -0.29
15 Rv0403c Probable conserved membrane protein MmpS1 -0.28
16 Rv1715 Probable 3-hydroxybutyryl-CoA dehydrogenase FadB3 (beta-hydroxybutyryl-CoA dehydrogenase) (BHBD) -0.28
17 Rv1036c Probable IS1560 transposase (fragment) -0.28
18 Rv0560c Possible benzoquinone methyltransferase (methylase) -0.27
19 Rv3432c Probable glutamate decarboxylase GadB -0.27
20 Rv3027c GCN5-related N-acetyltransferase -0.27

Or look for positive cofitness