Negative cofitness for Rv1544 from Mycobacterium tuberculosis H37Rv

Possible ketoacyl reductase
SEED: PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE (EC 1.-.-.-)

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv2589 4-aminobutyrate aminotransferase GabT (gamma-amino-N-butyrate transaminase) (GABA transaminase) (glutamate:succinic semialdehyde transaminase) (GABA aminotransferase) (GABA-at) -0.51
2 Rv3319 Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogenase) (fumaric hydrogenase) -0.43
3 Rv1426c Probable esterase LipO -0.39
4 Rv2271 Conserved hypothetical protein -0.36
5 Rv0125 Probable serine protease PepA (serine proteinase) (MTB32A) -0.34
6 Rv2590 Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) -0.33
7 Rv0178 Probable conserved Mce associated membrane protein -0.32
8 Rv2691 TRK system potassium uptake protein CeoB -0.31
9 Rv0578c PE-PGRS family protein PE_PGRS7 -0.31
10 Rv1820 Probable acetolactate synthase IlvG (acetohydroxy-acid synthase)(ALS) -0.31
11 Rv0386 Probable transcriptional regulatory protein (probably LuxR/UhpA-family) -0.31
12 Rv2045c Carboxylesterase LipT -0.30
13 Rv3803c Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C) -0.30
14 Rv2694c Conserved protein -0.30
15 Rv3388 PE-PGRS family protein PE_PGRS52 -0.30
16 Rv1428c Conserved hypothetical protein -0.30
17 Rv1640c Lysyl-tRNA synthetase 2 LysX -0.29
18 Rv2467 Probable aminopeptidase N PepN (Lysyl aminopeptidase) (LYS-AP) (alanine aminopeptidase) -0.28
19 Rv1318c Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) -0.28
20 Rv1244 Probable lipoprotein LpqZ -0.28

Or look for positive cofitness