Negative cofitness for Rv1246c from Mycobacterium tuberculosis H37Rv

Toxin RelE
SEED: RelE/StbE replicon stabilization toxin

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Rv0264c		Conserved hypothetical protein	-0.27
2	Rv3520c		Possible coenzyme F420-dependent oxidoreductase	-0.24
3	Rv3911		Possible alternative RNA polymerase sigma factor SigM	-0.23
4	Rv2226		Conserved protein	-0.23
5	Rv0791c		Conserved protein	-0.21
6	Rv3872		PE family-related protein PE35	-0.21
7	Rv3397c		Probable phytoene synthase PhyA	-0.21
8	Rv1193		Probable fatty-acid-CoA ligase FadD36 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	-0.21
9	Rv2670c		Conserved hypothetical protein	-0.20
10	Rv0755A		Putative transposase (fragment)	-0.20
11	Rv1992c		Probable metal cation transporter P-type ATPase G CtpG	-0.20
12	Rv0321		Probable deoxycytidine triphosphate deaminase Dcd (dCTP deaminase)	-0.20
13	Rv3880c		ESX-1 secretion-associated protein EspL	-0.20
14	Rv2352c		PPE family protein PPE38	-0.19
15	Rv0445c		Alternative RNA polymerase sigma factor SigK	-0.19
16	Rv3156		Probable NADH dehydrogenase I (chain L) NuoL (NADH-ubiquinone oxidoreductase chain L)	-0.19
17	Rv1580c		Probable PhiRv1 phage protein	-0.19
18	Rv1112		Probable GTP binding protein	-0.19
19	Rv0217c		Possible esterase LipW	-0.19
20	Rv0222		Probable enoyl-CoA hydratase EchA1 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase)	-0.19

Or look for positive cofitness