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  • Negative cofitness for Rv1069c from Mycobacterium tuberculosis H37Rv

    Conserved protein
    SEED: FIG01329746: membrane protein

    Computing cofitness values with 236 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 Rv1020 Probable transcription-repair coupling factor Mfd (TRCF) -0.39
    2 Rv0022c Probable transcriptional regulatory protein WhiB-like WhiB5 -0.34
    3 Rv0694 Possible L-lactate dehydrogenase (cytochrome) LldD1 -0.33
    4 Rv1974 Probable conserved membrane protein -0.33
    5 Rv1182 Probable conserved polyketide synthase associated protein PapA3 -0.30
    6 Rv3485c Probable short-chain type dehydrogenase/reductase -0.29
    7 Rv1277 Conserved hypothetical protein -0.28
    8 Rv1200 Probable conserved integral membrane transport protein -0.28
    9 Rv0692 Conserved hypothetical protein -0.28
    10 Rv1194c Conserved protein -0.28
    11 Rv0159c PE family protein PE3 -0.27
    12 Rv0456c enoyl-CoA hydratase EchA2 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) -0.27
    13 Rv0696 Probable membrane sugar transferase -0.27
    14 Rv0403c Probable conserved membrane protein MmpS1 -0.26
    15 Rv3202c Possible ATP-dependent DNA helicase -0.26
    16 Rv0937c DNA end-binding protein, Mku -0.26
    17 Rv3059 Probable cytochrome P450 136 Cyp136 -0.26
    18 Rv2456c Probable conserved integral membrane transport protein -0.26
    19 Rv0445c Alternative RNA polymerase sigma factor SigK -0.26
    20 Rv0428c GCN5-related N-acetyltransferase -0.26

    Or look for positive cofitness