Negative cofitness for Rv0825c from Mycobacterium tuberculosis H37Rv

Conserved protein
SEED: Transcriptional regulator, TetR family

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv1185c Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) -0.33
2 Rv1176c Conserved hypothetical protein -0.32
3 Rv3825c Polyketide synthase Pks2 -0.32
4 Rv3824c Conserved polyketide synthase associated protein PapA1 -0.30
5 Rv2824c Hypothetical protein -0.28
6 Rv3820c Possible conserved polyketide synthase associated protein PapA2 -0.27
7 Rv0295c Conserved protein -0.27
8 Rv2929 Hypothetical protein -0.26
9 Rv3826 Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) -0.26
10 Rv1632c Hypothetical protein -0.25
11 Rv0551c Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) -0.25
12 Rv2721c Possible conserved transmembrane alanine and glycine rich protein -0.25
13 Rv3450c ESX conserved component EccB4. ESX-4 type VII secretion system protein. Probable membrane protein. -0.24
14 Rv0554 Possible peroxidase BpoC (non-haem peroxidase) -0.24
15 Rv0692 Conserved hypothetical protein -0.24
16 Rv1387 PPE family protein PPE20 -0.24
17 Rv1814 Membrane-bound C-5 sterol desaturase Erg3 (sterol-C5-desaturase) -0.24
18 Rv0786c Conserved protein -0.24
19 Rv3198c Probable ATP-dependent DNA helicase II UvrD2 -0.24
20 Rv1504c Conserved hypothetical protein -0.23

Or look for positive cofitness