Negative cofitness for Rv0644c from Mycobacterium tuberculosis H37Rv

Methoxy mycolic acid synthase 2 MmaA2 (methyl mycolic acid synthase 2) (MMA2) (hydroxy mycolic acid synthase)
SEED: Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)
KEGG: cyclopropane-fatty-acyl-phospholipid synthase

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv1824 Conserved hypothetical membrane protein -0.31
2 Rv1823 Conserved protein -0.30
3 Rv1635c Probable mannosyltransferase. Probable conserved transmembrane protein. -0.28
4 Rv0012 Probable conserved membrane protein -0.28
5 Rv2546 Possible toxin VapC18 -0.27
6 Rv0265c Probable periplasmic iron-transport lipoprotein -0.26
7 Rv3586 Conserved hypothetical protein -0.26
8 Rv0307c Unknown protein -0.24
9 Rv3667 Acetyl-coenzyme A synthetase Acs (acetate--CoA ligase) (acetyl-CoA synthetase) (acetyl-CoA synthase) (acyl-activating enzyme) (acetate thiokinase) (acetyl-activating enzyme) (acetate--coenzyme A ligase) (acetyl-coenzyme A synthase) -0.24
10 Rv3616c ESX-1 secretion-associated protein A, EspA -0.24
11 Rv0885 Conserved hypothetical protein -0.24
12 Rv2394 Probable gamma-glutamyltranspeptidase precursor GgtB (gamma-glutamyltransferase) (glutamyl transpeptidase) -0.24
13 Rv0241c Probable 3-hydroxyacyl-thioester dehydratase HtdX -0.23
14 Rv1825 Conserved protein -0.23
15 Rv3685c Probable cytochrome P450 137 Cyp137 -0.23
16 Rv0634A Unknown protein -0.23
17 Rv2114 Conserved protein -0.22
18 Rv3698 Conserved protein -0.21
19 Rv3511 PE-PGRS family protein PE_PGRS55 -0.21
20 Rv3521 Conserved hypothetical protein -0.21

Or look for positive cofitness