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  • Negative cofitness for Rv0427c from Mycobacterium tuberculosis H37Rv

    Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)
    SEED: Exodeoxyribonuclease III (EC 3.1.11.2)
    KEGG: exodeoxyribonuclease III

    Computing cofitness values with 236 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 Rv3517 Conserved hypothetical protein -0.25
    2 Rv2124c 5-methyltetrahydrofolate--homocystein methyltransferase MetH (methionine synthase, vitamin-B12 dependent isozyme) (ms) -0.24
    3 Rv2749 Conserved protein -0.23
    4 Rv2549c Possible toxin VapC20 -0.23
    5 Rv3705c Conserved protein -0.23
    6 Rv2312 Hypothetical protein -0.23
    7 Rv2788 Probable transcriptional repressor SirR -0.23
    8 Rv0047c Conserved protein -0.23
    9 Rv1118c Conserved protein -0.22
    10 Rv0194 Probable transmembrane multidrug efflux pump -0.22
    11 Rv3732 Conserved protein -0.22
    12 Rv0544c Possible conserved transmembrane protein -0.21
    13 Rv0614 Conserved hypothetical protein -0.21
    14 Rv0919 GCN5-related N-acetyltransferase -0.20
    15 Rv0835 Possible lipoprotein LpqQ -0.20
    16 Rv0545c Probable low-affinity inorganic phosphate transporter integral membrane protein PitA -0.20
    17 Rv1562c Maltooligosyltrehalose trehalohydrolase TreZ -0.20
    18 Rv3711c Probable DNA polymerase III (epsilon subunit) DnaQ -0.20
    19 Rv1498c Probable methyltransferase -0.19
    20 Rv3591c Possible hydrolase -0.19

    Or look for positive cofitness