Negative cofitness for Rv0266c from Mycobacterium tuberculosis H37Rv

Probable 5-oxoprolinase OplA (5-oxo-L-prolinase) (pyroglutamase) (5-OPASE)

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Rv0916c		PE family protein PE7	-0.29
2	Rv2254c		Probable integral membrane protein	-0.28
3	Rv3451		Probable cutinase precursor Cut3	-0.27
4	Rv0569		Conserved protein	-0.27
5	Rv3836		Conserved hypothetical protein	-0.27
6	Rv0895		Possible triacylglycerol synthase (diacylglycerol acyltransferase)	-0.27
7	Rv1359		Probable transcriptional regulatory protein	-0.26
8	Rv3476c		Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter)	-0.26
9	Rv1218c		Probable tetronasin-transport ATP-binding protein ABC transporter	-0.25
10	Rv0669c		Possible hydrolase	-0.25
11	Rv0428c		GCN5-related N-acetyltransferase	-0.24
12	Rv3198c		Probable ATP-dependent DNA helicase II UvrD2	-0.23
13	Rv2503c		Probable succinyl-CoA:3-ketoacid-coenzyme A transferase (beta subunit) ScoB (3-oxo-acid:CoA transferase) (OXCT B) (succinyl CoA:3-oxoacid CoA-transferase)	-0.23
14	Rv0625c		Probable conserved transmembrane protein	-0.23
15	Rv0694		Possible L-lactate dehydrogenase (cytochrome) LldD1	-0.23
16	Rv0922		Possible transposase	-0.23
17	Rv1051c		Conserved hypothetical protein	-0.23
18	Rv0904c		Putative acetyl-coenzyme A carboxylase carboxyl transferase (subunit beta) AccD3 (accase beta chain)	-0.22
19	Rv3557c		Transcriptional regulatory protein (probably TetR-family)	-0.22
20	Rv0674		Conserved hypothetical protein	-0.22

Or look for positive cofitness