Negative cofitness for Rv0241c from Mycobacterium tuberculosis H37Rv

Probable 3-hydroxyacyl-thioester dehydratase HtdX
SEED: Acyl dehydratase

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv1723 Probable hydrolase -0.33
2 Rv0554 Possible peroxidase BpoC (non-haem peroxidase) -0.33
3 Rv3263 Probable DNA methylase (modification methylase) (methyltransferase) -0.32
4 Rv2506 Probable transcriptional regulatory protein (probably TetR-family) -0.31
5 Rv3397c Probable phytoene synthase PhyA -0.31
6 Rv0789c Hypothetical protein -0.30
7 Rv0117 Oxidative stress response regulatory protein OxyS -0.30
8 Rv2427c Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase) -0.29
9 Rv3765c Probable two component transcriptional regulatory protein TcrX -0.28
10 Rv2929 Hypothetical protein -0.28
11 Rv1205 Conserved hypothetical protein -0.28
12 Rv2902c Probable ribonuclease HII protein RnhB (RNase HII) -0.28
13 Rv0295c Conserved protein -0.27
14 Rv2721c Possible conserved transmembrane alanine and glycine rich protein -0.26
15 Rv3198c Probable ATP-dependent DNA helicase II UvrD2 -0.26
16 Rv2758c Possible antitoxin VapB21 -0.26
17 Rv0190 Conserved protein -0.26
18 Rv0160c PE family protein PE4 -0.25
19 Rv3173c Probable transcriptional regulatory protein (probably TetR/AcrR-family) -0.25
20 Rv2893 Possible oxidoreductase -0.25

Or look for positive cofitness