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  • Negative cofitness for Rv0162c from Mycobacterium tuberculosis H37Rv

    Probable zinc-type alcohol dehydrogenase (E subunit) AdhE1
    SEED: Alcohol dehydrogenase (EC 1.1.1.1)
    KEGG: alcohol dehydrogenase

    Computing cofitness values with 236 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 Rv2561 Conserved hypothetical protein -0.26
    2 Rv3830c Transcriptional regulatory protein (probably TetR-family) -0.26
    3 Rv0277c Possible toxin VapC25. Contains PIN domain. -0.25
    4 Rv3514 PE-PGRS family protein PE_PGRS57 -0.25
    5 Rv0586 Probable transcriptional regulatory protein Mce2R (GntR-family) -0.24
    6 Rv2964 Probable formyltetrahydrofolate deformylase PurU (formyl-FH(4) hydrolase) -0.22
    7 Rv2709 Probable conserved transmembrane protein -0.22
    8 Rv1944c Conserved protein -0.22
    9 Rv0499 Conserved hypothetical protein -0.21
    10 Rv0348 Possible transcriptional regulatory protein -0.21
    11 Rv3225c GCN5-related N-acetyltransferase, phosphorylase -0.21
    12 Rv3683 Conserved protein -0.21
    13 Rv1396c PE-PGRS family protein PE_PGRS25 -0.21
    14 Rv2970A Conserved hypothetical protein -0.21
    15 Rv2030c Conserved protein -0.21
    16 Rv3388 PE-PGRS family protein PE_PGRS52 -0.20
    17 Rv0303 Probable dehydrogenase/reductase -0.20
    18 Rv2446c Probable conserved integral membrane protein -0.20
    19 Rv2831 Probable enoyl-CoA hydratase EchA16 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) -0.20
    20 Rv2276 Cytochrome P450 121 Cyp121 -0.20

    Or look for positive cofitness