Negative cofitness for Rv0037c from Mycobacterium tuberculosis H37Rv

Probable conserved integral membrane protein
SEED: Possible membrane protein

Computing cofitness values with 236 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Rv1181 Probable polyketide beta-ketoacyl synthase Pks4 -0.46
2 Rv3826 Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) -0.44
3 Rv3825c Polyketide synthase Pks2 -0.43
4 Rv3820c Possible conserved polyketide synthase associated protein PapA2 -0.43
5 Rv2344c Probable deoxyguanosine triphosphate triphosphohydrolase Dgt (dGTPase) (dGTP triphosphohydrolase) -0.40
6 Rv2498c Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) -0.39
7 Rv3824c Conserved polyketide synthase associated protein PapA1 -0.38
8 Rv3871 ESX conserved component EccCb1. ESX-1 type VII secretion system protein. -0.37
9 Rv2569c Conserved hypothetical protein -0.36
10 Rv0295c Conserved protein -0.36
11 Rv2709 Probable conserved transmembrane protein -0.35
12 Rv3201c Probable ATP-dependent DNA helicase -0.35
13 Rv1182 Probable conserved polyketide synthase associated protein PapA3 -0.35
14 Rv1180 Probable polyketide beta-ketoacyl synthase Pks3 -0.35
15 Rv2912c Probable transcriptional regulatory protein (probably TetR-family) -0.33
16 Rv1185c Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) -0.33
17 Rv1108c Probable exodeoxyribonuclease VII (large subunit) XseA (exonuclease VII large subunit) -0.33
18 Rv0530A Conserved protein -0.33
19 Rv3202c Possible ATP-dependent DNA helicase -0.33
20 Rv3777 Probable oxidoreductase -0.32

Or look for positive cofitness