Negative cofitness for Psyr_2436 from Pseudomonas syringae pv. syringae B728a

Mannitol dehydrogenase
SEED: Multiple polyol-specific dehydrogenase (EC 1.1.1.-)

Computing cofitness values with 193 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psyr_4339		ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Histidine kinase:Histidine kinase	-0.45
2	Psyr_4519		General substrate transporter:Major facilitator superfamily	-0.42
3	Psyr_1868		hypothetical protein	-0.42
4	Psyr_2411		Short-chain dehydrogenase/reductase SDR	-0.42
5	Psyr_1117		porin, OprB family	-0.42
6	Psyr_1792		Amino acid adenylation	-0.41
7	Psyr_2333		Binding-protein-dependent transport systems inner membrane component	-0.41
8	Psyr_0992		Protein of unknown function DUF1329	-0.41
9	Psyr_1407		Protein of unknown function DUF28	-0.39
10	Psyr_2829		conserved hypothetical protein	-0.38
11	Psyr_1892		Short-chain dehydrogenase/reductase SDR	-0.38
12	Psyr_0723		Sensor protein PilS	-0.38
13	Psyr_2085		methylisocitrate lyase	-0.38
14	Psyr_3796		transcriptional regulator, LysR family	-0.37
15	Psyr_5067		conserved hypothetical protein	-0.37
16	Psyr_5081		Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:Heavy metal translocating P-type ATPase	-0.37
17	Psyr_2311		conserved hypothetical protein	-0.36
18	Psyr_1041		transcriptional regulator, AraC family	-0.36
19	Psyr_2185		Prokaryotic protein of unknown function DUF849	-0.36
20	Psyr_2331		FAD-dependent pyridine nucleotide-disulfide oxidoreductase:BFD-like [2Fe-2S]-binding region	-0.36

Or look for positive cofitness