Negative cofitness for Psyr_1043 from Pseudomonas syringae pv. syringae B728a

D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein
SEED: Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-)
KEGG: gluconate 2-dehydrogenase

Computing cofitness values with 193 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psyr_0263		Two-component response regulator AlgB	-0.42
2	Psyr_1868		hypothetical protein	-0.37
3	Psyr_2150		protein of unknown function DUF903	-0.37
4	Psyr_3407		conserved hypothetical protein	-0.35
5	Psyr_4519		General substrate transporter:Major facilitator superfamily	-0.35
6	Psyr_0177		adenylate cyclase	-0.34
7	Psyr_1104		Heme oxygenase	-0.34
8	Psyr_3829		Leucine-rich repeat protein	-0.33
9	Psyr_2681		gamma-glutamyltransferase 2, Threonine peptidase, MEROPS family T03	-0.33
10	Psyr_3763		GGDEF domain protein	-0.33
11	Psyr_3149		General secretion pathway protein G	-0.32
12	Psyr_1654		Type IV pilus assembly PilZ	-0.32
13	Psyr_1236		transcriptional regulator, BadM/Rrf2 family	-0.32
14	Psyr_2176		Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal	-0.32
15	Psyr_3989		hypothetical protein	-0.32
16	Psyr_4339		ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Histidine kinase:Histidine kinase	-0.31
17	Psyr_3214		Propeptide, PepSY amd peptidase M4	-0.31
18	Psyr_2978		PAS	-0.31
19	Psyr_1890		type III effector HopAP1	-0.31
20	Psyr_4432		Urease, gamma subunit	-0.30

Or look for positive cofitness