Negative cofitness for Psyr_0451 from Pseudomonas syringae pv. syringae B728a

regulatory protein, LysR:LysR, substrate-binding protein
SEED: Malonate utilization transcriptional regulator
KEGG: LysR family transcriptional regulator, malonate utilization transcriptional regulator

Computing cofitness values with 193 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Psyr_4844		HAD-superfamily hydrolase, subfamily IB (PSPase-like):HAD-superfamily subfamily IB hydrolase, hypothetical 2	-0.51
2	Psyr_1965		Twin-arginine translocation pathway signal	-0.51
3	Psyr_0544		hydroxymethylpyrimidine synthase	-0.50
4	Psyr_4896		imidazole glycerol phosphate synthase subunit hisH	-0.49
5	Psyr_4894		1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	-0.49
6	Psyr_4134		ATP phosphoribosyltransferase (homohexameric)	-0.47
7	Psyr_4132		histidinol phosphate aminotransferase apoenzyme	-0.47
8	Psyr_0832		Two-component sensor kinase CbrA	-0.46
9	Psyr_0827		pantothenate synthetase	-0.45
10	Psyr_1933		hypothetical protein	-0.44
11	Psyr_0469		dihydroxyacid dehydratase	-0.44
12	Psyr_4897		imidazoleglycerol-phosphate dehydratase	-0.44
13	Psyr_3690		formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase	-0.44
14	Psyr_1257		2-isopropylmalate synthase	-0.44
15	Psyr_4236		extracellular solute-binding protein, family 5	-0.44
16	Psyr_4133		histidinol dehydrogenase	-0.43
17	Psyr_2077		regulatory protein, LysR:LysR, substrate-binding protein	-0.43
18	Psyr_0846		acetolactate synthase, large subunit	-0.43
19	Psyr_4573		Histidine triad (HIT) protein	-0.43
20	Psyr_0847		acetolactate synthase, small subunit	-0.43

Or look for positive cofitness