Negative cofitness for Pf6N2E2_759 from Pseudomonas fluorescens FW300-N2E2

HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)
SEED: HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Pf6N2E2_3676		Phosphodiesterase/alkaline phosphatase D-like	-0.33
2	Pf6N2E2_3456		Inner membrane protein YfiN	-0.32
3	Pf6N2E2_4031		Biofilm PGA outer membrane secretin PgaA	-0.32
4	Pf6N2E2_4030		Biofilm PGA synthesis deacetylase PgaB (EC 3.-)	-0.29
5	Pf6N2E2_4028		Biofilm PGA synthesis auxiliary protein PgaD	-0.29
6	Pf6N2E2_4193		Signal transduction histidine kinase	-0.29
7	Pf6N2E2_6078		Xaa-Pro aminopeptidase (EC 3.4.11.9)	-0.27
8	Pf6N2E2_4194		Two-component response regulator	-0.27
9	Pf6N2E2_4032		hypothetical protein	-0.26
10	Pf6N2E2_3309		Outer membrane porin, OprD family	-0.26
11	Pf6N2E2_3303		Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-)	-0.26
12	Pf6N2E2_3316		Fe-S oxidoreductase	-0.25
13	Pf6N2E2_5593		Leucyl-tRNA synthetase	-0.25
14	Pf6N2E2_1703		Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1)	-0.25
15	Pf6N2E2_3317		Ornithine cyclodeaminase (EC 4.3.1.12)	-0.24
16	Pf6N2E2_791		hypothetical protein	-0.24
17	Pf6N2E2_3944		Protein of unknown function DUF81	-0.24
18	Pf6N2E2_3318		putative non-ribosomal peptide synthetase	-0.24
19	Pf6N2E2_94		Cyn operon transcriptional activator	-0.24
20	Pf6N2E2_4734		Acyltransferase family protein	-0.24

Or look for positive cofitness