Negative cofitness for Pf6N2E2_5366 from Pseudomonas fluorescens FW300-N2E2

DNA-binding heavy metal response regulator
SEED: DNA-binding heavy metal response regulator
KEGG: two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Pf6N2E2_5436		MutT/nudix family protein	-0.32
2	Pf6N2E2_4889		Putative transport protein	-0.32
3	Pf6N2E2_3850		FIG074102: hypothetical protein	-0.32
4	Pf6N2E2_5814		Glutaredoxin	-0.30
5	Pf6N2E2_1630		COG1020: Non-ribosomal peptide synthetase modules and related proteins	-0.29
6	Pf6N2E2_3951		Efflux transporter, RND family, MFP subunit	-0.28
7	Pf6N2E2_4519		Penicillin acylase II (EC 3.5.1.11)	-0.28
8	Pf6N2E2_1564		3-dehydroquinate synthase (EC 4.2.3.4)	-0.28
9	Pf6N2E2_2312		Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1)	-0.28
10	Pf6N2E2_486		TRAP-type C4-dicarboxylate transport system, small permease component	-0.28
11	Pf6N2E2_4154		diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)	-0.27
12	Pf6N2E2_188		Formamidase (EC 3.5.1.49)	-0.27
13	Pf6N2E2_441		FIG00958773: hypothetical protein	-0.27
14	Pf6N2E2_5840		hypothetical protein	-0.26
15	Pf6N2E2_4757		DNA-binding domain of ModE / Molybdate-binding domain of ModE	-0.26
16	Pf6N2E2_4153		Sensory box histidine kinase	-0.26
17	Pf6N2E2_5028		Ribosomal large subunit pseudouridine synthase E (EC 4.2.1.70)	-0.26
18	Pf6N2E2_4588		COG2363	-0.26
19	Pf6N2E2_5238		Tryptophan synthase beta chain like (EC 4.2.1.20)	-0.26
20	Pf6N2E2_149		Inner membrane component of tripartite multidrug resistance system	-0.26

Or look for positive cofitness