Negative cofitness for Pf6N2E2_453 from Pseudomonas fluorescens FW300-N2E2

LysR family transcriptional regulator STM2281
SEED: LysR family transcriptional regulator STM2281

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Pf6N2E2_4154 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) -0.41
2 Pf6N2E2_1718 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) -0.34
3 Pf6N2E2_5059 Transcriptional regulator, TetR family -0.33
4 Pf6N2E2_5006 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) -0.33
5 Pf6N2E2_5156 Two-component sensor CbrB: intrcellular carbon:nitrogen balance -0.32
6 Pf6N2E2_149 Inner membrane component of tripartite multidrug resistance system -0.32
7 Pf6N2E2_4519 Penicillin acylase II (EC 3.5.1.11) -0.31
8 Pf6N2E2_4132 L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1) -0.31
9 Pf6N2E2_5468 Nudix hydrolase family protein PA3470 -0.31
10 Pf6N2E2_3856 Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) -0.30
11 Pf6N2E2_4009 GGDEF domain protein -0.29
12 Pf6N2E2_148 Membrane fusion component of tripartite multidrug resistance system -0.29
13 Pf6N2E2_5176 Acetolactate synthase small subunit (EC 2.2.1.6) -0.29
14 Pf6N2E2_5083 Serine hydroxymethyltransferase (EC 2.1.2.1) -0.28
15 Pf6N2E2_3647 LysR family transcriptional regulator PA4989 -0.28
16 Pf6N2E2_4554 Thiol-disulfide isomerase and thioredoxins -0.28
17 Pf6N2E2_4417 Protein of unknown function DUF484 -0.28
18 Pf6N2E2_5579 Ornithine carbamoyltransferase (EC 2.1.3.3) -0.28
19 Pf6N2E2_4117 FIG00960078: hypothetical protein -0.28
20 Pf6N2E2_3460 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) -0.28

Or look for positive cofitness