Negative cofitness for Pf6N2E2_4 from Pseudomonas fluorescens FW300-N2E2

Non-ribosomal peptide synthetase modules, pyoverdine @ Siderophore biosynthesis non-ribosomal peptide synthetase modules

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Pf6N2E2_1270		Heavy metal RND efflux outer membrane protein, CzcC family	-0.52
2	Pf6N2E2_1272		Acriflavin resistance plasma membrane protein	-0.50
3	Pf6N2E2_1271		Acriflavin resistance plasma membrane protein	-0.47
4	Pf6N2E2_1087		Iron siderophore sensor protein	-0.44
5	Pf6N2E2_1273		Probable RND efflux membrane fusion protein	-0.43
6	Pf6N2E2_5619		Putative two-component system sensor kinase	-0.43
7	Pf6N2E2_5621		DNA-binding response regulator	-0.40
8	Pf6N2E2_1633		Iron(III) dicitrate transport system permease protein FecD (TC 3.A.1.14.1)	-0.40
9	Pf6N2E2_4046		FIG00953482: hypothetical protein	-0.36
10	Pf6N2E2_1635		ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components	-0.33
11	Pf6N2E2_2754		Sigma factor RpoE negative regulatory protein RseB precursor	-0.33
12	Pf6N2E2_1634		ABC-type Fe3+-siderophore transport system, permease component	-0.32
13	Pf6N2E2_1632		Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1)	-0.32
14	Pf6N2E2_1626		Putative ATP-binding component of a transport system	-0.31
15	Pf6N2E2_4433		Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives)	-0.31
16	Pf6N2E2_773		Undecaprenyl-diphosphatase (EC 3.6.1.27)	-0.30
17	Pf6N2E2_5097		FIG00953595: hypothetical protein	-0.30
18	Pf6N2E2_1636		Ferrichrome-iron receptor	-0.29
19	Pf6N2E2_3243		FIG067310: hypothetical protein	-0.29
20	Pf6N2E2_2902		TonB-dependent hemin , ferrichrome receptor	-0.27

Or look for positive cofitness