Negative cofitness for Pf6N2E2_3773 from Pseudomonas fluorescens FW300-N2E2

Poly(3-hydroxyalkanoate) depolymerase
SEED: Poly(3-hydroxyalkanoate) depolymerase

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Pf6N2E2_4602 Twitching motility protein PilT -0.27
2 Pf6N2E2_5710 probable membrane protein YPO2362 -0.24
3 Pf6N2E2_285 FIG002903: a protein of unknown function perhaps involved in purine metabolism -0.22
4 Pf6N2E2_2031 Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) -0.21
5 Pf6N2E2_3407 putative solute-binding component of ABC transporter -0.21
6 Pf6N2E2_2875 Lysophospholipase (EC 3.1.1.5); Monoglyceride lipase (EC 3.1.1.23); putative -0.20
7 Pf6N2E2_4433 Uncharacterized protein EC-HemY, likely associated with heme metabolism based on gene clustering with hemC, hemD in Proteobacteria (unrelated to HemY-type PPO in GramPositives) -0.19
8 Pf6N2E2_5088 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) -0.19
9 Pf6N2E2_861 Transcriptional regulator, LysR family -0.18
10 Pf6N2E2_4434 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation -0.18
11 Pf6N2E2_587 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) -0.18
12 Pf6N2E2_4769 Acyl-CoA dehydrogenase (EC 1.3.8.7) -0.18
13 Pf6N2E2_600 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases -0.18
14 Pf6N2E2_578 Mobile element protein -0.18
15 Pf6N2E2_2452 Spermidine synthase (EC 2.5.1.16) -0.18
16 Pf6N2E2_1291 Ferrichrome-iron receptor -0.18
17 Pf6N2E2_383 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) -0.17
18 Pf6N2E2_2872 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) -0.17
19 Pf6N2E2_1081 probable membrane protein YPO3302 -0.17
20 Pf6N2E2_3563 FMN-dependent NADH-azoreductase -0.17

Or look for positive cofitness