Negative cofitness for Pf6N2E2_2267 from Pseudomonas fluorescens FW300-N2E2

Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)
SEED: Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)
KEGG: two-component system, OmpR family, heavy metal sensor histidine kinase CusS

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Pf6N2E2_4029 Biofilm PGA synthesis N-glycosyltransferase PgaC (EC 2.4.-.-) -0.30
2 Pf6N2E2_4031 Biofilm PGA outer membrane secretin PgaA -0.29
3 Pf6N2E2_4030 Biofilm PGA synthesis deacetylase PgaB (EC 3.-) -0.27
4 Pf6N2E2_1175 VgrG protein -0.27
5 Pf6N2E2_5549 Copper resistance protein D -0.27
6 Pf6N2E2_2414 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 -0.26
7 Pf6N2E2_4634 Protein yceI precursor -0.26
8 Pf6N2E2_5865 Chaperone protein HtpG -0.26
9 Pf6N2E2_1176 Mll2356 protein -0.25
10 Pf6N2E2_2587 Serine phosphatase RsbU, regulator of sigma subunit -0.25
11 Pf6N2E2_885 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) -0.25
12 Pf6N2E2_3944 Protein of unknown function DUF81 -0.24
13 Pf6N2E2_5702 Dienelactone hydrolase family -0.24
14 Pf6N2E2_3109 Outer membrane lipoprotein omp16 precursor -0.24
15 Pf6N2E2_3978 Type I secretion system, membrane fusion protein LapC -0.24
16 Pf6N2E2_3980 Type I secretion system, outer membrane component LapE -0.24
17 Pf6N2E2_4341 IcmF-related protein -0.23
18 Pf6N2E2_4926 hypothetical protein -0.23
19 Pf6N2E2_795 ABC transporter ATP-binding protein uup -0.23
20 Pf6N2E2_4011 Sensory box/GGDEF family protein -0.23

Or look for positive cofitness