Negative cofitness for Pf6N2E2_2000 from Pseudomonas fluorescens FW300-N2E2

Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
SEED: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	Pf6N2E2_4009		GGDEF domain protein	-0.28
2	Pf6N2E2_1654		Oxidoreductase, short chain dehydrogenase/reductase family	-0.27
3	Pf6N2E2_1581		Type I secretion outer membrane protein, TolC precursor	-0.26
4	Pf6N2E2_136		Glycolate dehydrogenase (EC 1.1.99.14), FAD-binding subunit GlcE	-0.25
5	Pf6N2E2_5925		Transglutaminase-like enzymes, putative cysteine proteases	-0.25
6	Pf6N2E2_5176		Acetolactate synthase small subunit (EC 2.2.1.6)	-0.24
7	Pf6N2E2_5579		Ornithine carbamoyltransferase (EC 2.1.3.3)	-0.24
8	Pf6N2E2_5156		Two-component sensor CbrB: intrcellular carbon:nitrogen balance	-0.24
9	Pf6N2E2_5175		Acetolactate synthase large subunit (EC 2.2.1.6)	-0.23
10	Pf6N2E2_4759		Biotin synthase (EC 2.8.1.6)	-0.23
11	Pf6N2E2_110		Cellobiose phosphotransferase system YdjC-like protein	-0.23
12	Pf6N2E2_2409		Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	-0.23
13	Pf6N2E2_3714		FIG017861: hypothetical protein	-0.23
14	Pf6N2E2_2535		FIG00954136: hypothetical protein	-0.23
15	Pf6N2E2_4047		Tryptophan synthase alpha chain (EC 4.2.1.20)	-0.22
16	Pf6N2E2_4442		FIG00957574: hypothetical protein	-0.22
17	Pf6N2E2_940		Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-0.22
18	Pf6N2E2_2075		Peptidase, U7 family	-0.22
19	Pf6N2E2_4768		Acyl-CoA dehydrogenase (EC 1.3.8.7)	-0.21
20	Pf6N2E2_4587		Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-)	-0.21

Or look for positive cofitness