Negative cofitness for Pf6N2E2_1978 from Pseudomonas fluorescens FW300-N2E2

DNA topoisomerase III (EC 5.99.1.2) in PFGI-1-like cluster
SEED: DNA topoisomerase III (EC 5.99.1.2) in PFGI-1-like cluster

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Pf6N2E2_80 gamma-glutamylputrescine oxidase (EC 1.4.3.-) (from data) -0.29
2 Pf6N2E2_5157 Two-component sensor CbrA: intrcellular carbon:nitrogen balance -0.28
3 Pf6N2E2_4514 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) -0.25
4 Pf6N2E2_5554 FIG023103: Predicted transmembrane protein -0.24
5 Pf6N2E2_5158 FIG00954153: hypothetical protein -0.24
6 Pf6N2E2_4512 Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19) (from data) -0.24
7 Pf6N2E2_3593 Protein containing domains DUF404, DUF407, DUF403 -0.23
8 Pf6N2E2_2044 Histidine kinase/response regulator hybrid protein -0.22
9 Pf6N2E2_376 Similar to non-heme chloroperoxidase, sll5080 homolog -0.22
10 Pf6N2E2_4383 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.99); 4-guanidinobutyraldehyde dehydrogenase (EC 1.2.1.54) (from data) -0.22
11 Pf6N2E2_1142 Polymyxin resistance protein ArnT, undecaprenyl phosphate-alpha-L-Ara4N transferase; Melittin resistance protein PqaB -0.22
12 Pf6N2E2_4516 Putrescine transport system permease protein PotH (TC 3.A.1.11.2) -0.22
13 Pf6N2E2_4513 Putrescine ABC transporter putrescine-binding protein PotF (TC 3.A.1.11.2) -0.22
14 Pf6N2E2_4515 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) -0.21
15 Pf6N2E2_688 Transcriptional regulator, LysR family -0.21
16 Pf6N2E2_3708 predicted biotin regulatory protein BioR (GntR family) -0.21
17 Pf6N2E2_2527 Oxidoreductase, short chain dehydrogenase/reductase family -0.21
18 Pf6N2E2_359 Opine oxidase subunit B -0.21
19 Pf6N2E2_2820 NADH:flavin oxidoreductases, Old Yellow Enzyme family -0.21
20 Pf6N2E2_5545 Queuosine Biosynthesis QueE Radical SAM -0.20

Or look for positive cofitness