Negative cofitness for Pf6N2E2_1041 from Pseudomonas fluorescens FW300-N2E2

Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
SEED: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)

Computing cofitness values with 388 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 Pf6N2E2_2226 Integral membrane protein TerC -0.27
2 Pf6N2E2_3275 FOG: TPR repeat -0.27
3 Pf6N2E2_4009 GGDEF domain protein -0.26
4 Pf6N2E2_5176 Acetolactate synthase small subunit (EC 2.2.1.6) -0.26
5 Pf6N2E2_5175 Acetolactate synthase large subunit (EC 2.2.1.6) -0.26
6 Pf6N2E2_1613 short-chain dehydrogenase/reductase -0.25
7 Pf6N2E2_71 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) -0.25
8 Pf6N2E2_1439 hypothetical protein -0.25
9 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) -0.24
10 Pf6N2E2_4826 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) -0.24
11 Pf6N2E2_3841 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) -0.24
12 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) -0.24
13 Pf6N2E2_4596 Homoserine O-acetyltransferase (EC 2.3.1.31) -0.24
14 Pf6N2E2_4825 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) -0.23
15 Pf6N2E2_4048 Tryptophan synthase beta chain (EC 4.2.1.20) -0.23
16 Pf6N2E2_4597 Homoserine O-acetyltransferase (EC 2.3.1.31) -0.23
17 Pf6N2E2_3842 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) -0.23
18 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) -0.23
19 Pf6N2E2_333 hypothetical protein -0.22
20 Pf6N2E2_3084 Ribosomal RNA large subunit methyltransferase A (EC 2.1.1.51) -0.22

Or look for positive cofitness